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Post Doc Researcher - Biochemistry (Mammalian Cell Culture) in Cambridgeshire

Role - 2 years fixed term.

Identify, develop and implement surface chemistries facilitating the immobilisation of bio recognition species on surfaces within Printed Electronic based point-of-care biosensors. Prepare and evaluate cultures of mammalian or bacterial cells to facilitate experiments towards the development of biosensors for these species. Accurately prepare stock solutions containing other biological analytes including proteins, DNA and metal ions, for use in biosensor evaluation. Optimise optical and/or electronic assay protocols to facilitate evaluation of novel biosensor device platforms, including preparation of labelled biomolecules for use as reporter species.  Modify surfaces within biosensor devices in order to minimise non-specific binding events and minimise surface bio-fouling.

Person:

A PhD in Biochemistry, Molecular Biology, Microbiology or Cell Biology, with excellent academic credentials and knowledge of these fields, is essential.

Experience of cell culture, manipulations of mammalian and/or bacterial cells and associated good microbiological practice (ascetic technique, etc.) is essential with experience of managing a laboratory environment in which this type of work is carried out would be highly desirable.

A working knowledge of biosensors and experience of running optical or electronic bio-assays for the quantitative assessment of biological binding to immobilised receptor species is also highly desirable.

Experience of chemical modification of surfaces for the attachment of biological recognition species (antibodies, DNA, etc.) and for development of non-fouling surfaces is desirable. 

Experience of other techniques used for quantitative detection or sorting of cells such as PCR and flow cytometry, or an in depth understanding of these techniques, is desirable.

Creative, inventive with an aptitude for experimental work and with experience of solving complex problems in the biochemical and/or biosensor field.

Self-motivated with the ability to operate independently in a laboratory environment.

Excellent team-working skills, with the ability to interface and effectively communicate across multiple scientific disciplines. 

An understanding of the time-critical demands of target-driven Industrial research and with drive and passion to work towards critical deadlines.

Reference

PTPOSTDOC

Location

Cambridgeshire
West of Cambridge

Salary

£25,000 to £35,000
£32k - £35k

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